Integral field spectroscopy of HII regions in M33

Integral field spectroscopy (IFS) is presented for star forming regions in M33. A central area of 300 x 500 pc^2 and the external HII region IC 132, at a galactocentric distance {\sim} 19arcmin (4.69 kpc) were observed with the Potsdam Multi Aperture Spectrophotometer (PMAS) instrument at the 3.5 m telescope of the Calar Alto Hispano- Alem\'an observatory (CAHA). The spectral coverage goes from 3600 A to 1{\mu}m to include from [OII]{\lambda}3727 A to the near infrared lines required for deriving sulphur electron temperature and abundance diagnostics. Local conditions within individual HII regions are presented in the form of emission line fluxes and physical conditions for each spatial resolution element (spaxel) and for segments with similar H{\alpha} surface brightness. A clear dichotomy is observed when comparing the central to outer disc HII regions. While the external HII region has higher electron temperature plus larger H{\beta} equivalent width, size and excitation, the central region has higher extinction and metal content. The dichotomy extends to the BPT diagnostic diagrams that show two orthogonal broad distributions of points. By comparing with pseudo-3D photoionization models we conclude that the bulk observed differences are probably related to a different ionization parameter and metallicity. Wolf-Rayet features are detected in IC 132, and resolved into two concentrations whose integrated spectra were used to estimate the characteristic number of WR stars. No WR features were detected in the central HII regions despite their higher metallicity.Comment: 72 pages, 37 figure

Ten years Center for Immersive Visualizations - Past, Present, and Future

Virtual Reality (VR) can be found in many fields. A majority of the time this involves the use of Head-Mounted Displays (HMDs). Their alternatives, large-scale immersive 3D screens and CAVE systems, can also be found in research and offer researchers high visual quality and collaborative VR experiences. This report covers the operation and learnings from maintaining a visualization center with large-scale immersive installations over the course of ten years

Plan de negocio: servicio de atención a mascotas caninas

Guau Express es una propuesta de negocios que busca ofrecer un servicio integral y especializado para atender a las mascotas caninas de aquellos dueños preocupados por su bienestar; realizando lo siguiente: conectando la necesidad de la mascota canina con la oferta de proveedores de servicios especializados, ofreciendo un servicio de transporte confiable y seguro para las mascotas desde su hogar hasta el proveedor de servicios veterinarios preferido o elegido por los dueños, y agregando valor a estos proveedores de servicios mediante la captación de clientes que les permita aumentar su volumen de negocio, con lo cual se busca dinamizar y facilitar la conexión entre los proveedores de servicios de mascotas caninas y los propios dueños

Remoción de carga orgánica en lixiviados por medio de un biofiltro empacado con residuos estabilizados

Los sitios de disposición final de residuos sólidos mal operados, causan afectaciones en su entorno y generan problemas de salud pública; estos sitios en general, son concebidos como pasivos ambientales. En el presente estudio se extrajeron residuos sólidos con edad superior a 8 años de la zona clausurada del relleno sanitario de la ciudad de Tuxtla Gutiérrez, Chiapas, México. Los residuos se caracterizaron con los parámetros de humedad, sólidos totales y sólidos volátiles, encontrando una alta estabilidad biológica en los mismos. Posteriormente, con el objetivo de evaluar el potencial biológico en el tratamiento de lixiviados, estos materiales fueron utilizados como lecho de empaque dentro de un biofiltro semi-aeróbico. Durante los ocho meses de monitoreo, el biofiltro registró eficiencias de remoción en DQO entre 60 y 90%, y alrededor de 60% en color, con cargas hidráulicas del orden de los 10-11 L/m3-d. Estos resultados representan de las primeras investigaciones en México usando como material de empaque residuos estabilizados, demostrando con ello, que los biofiltros pueden ser utilizados como una alternativa atractiva para el pretratamiento de lixiviados de rellenos sanitarios

Trochoidal Milling Path with Variable Feed. Application to the Machining of a Ti-6Al-4V Part

Trochoidal milling is a well-stablished machining strategy which still allows for the introduction of new approaches. This strategy can be applied to any kind of material, although it is usually associated to advanced materials, such as titanium and nickel alloys. This study is based on the adaptation of the feed speed of a milling tool with Ti-6Al-4V, so the chip width can be maintained constant without modifying the path geometry. A singularity in the experimental stage was to mill an Archimedes spiral groove instead of the conventional straight grooves. This made it possible to obtain a concave wall as well as a convex one and to optimize the amount of material used. The time efficiency compared to a constant feed, was slightly superior to 20%, reducing tool wear also. These techniques require milling machines with high mechanical and kinematic performance, as well as the absence of clearance between joints and a high acceleration capacity

Broad virus inactivation using inorganic micro/nano-particulate materials

Inorganic materials can provide a set of tools to decontaminate solid, liquid or air containing viral particles. The use of disinfectants can be limited or not practical in scenarios where continuous cleaning is not feasible. Physicochemical differences between viruses raise the need for effective formulations for all kind of viruses. In the present work we describe two types of antimicrobial inorganic materials: i) a novel soda-lime glass (G3), and ii) kaolin containing metals nanoparticles (Ag or CuO), as materials to disable virus infectivity. Strong antiviral properties can be observed in G3 glass, and kaolin-containing nanoparticle materials showing a reduction of viral infectivity close to 99%. in the first 10 ​min of contact of vesicular stomatitis virus (VSV). A potent virucidal activity is also present in G3 and kaolin containing Ag or CuO nanoparticles against all kinds of viruses tested, reducing more than 99% the amount of HSV-1, Adenovirus, VSV, Influenza virus and SARS-CoV-2 exposed to them. Virucidal properties could be explained by a direct interaction of materials with viruses as well as inactivation by the presence of virucidal elements in the material lixiviates. Kaolin-based materials guarantee a controlled release of active nanoparticles with antiviral activity. Current coronavirus crisis highlights the need for new strategies to remove viruses from contaminated areas. We propose these low-cost inorganic materials as useful disinfecting antivirals in the actual or future pandemic threats.This research was performed with support from The Spanish National Research Council (CSIC) (Project No 202060E109). M.F. is grateful to the Comunidad Autonoma de Madrid for research project No. 2017-T1/BIO-4992 (“Atracción de Talento” Action) cofunded by Universidad Complutense de Madrid. This publication was also supported by the European Virus Archive GLOBAL (EVA-GLOBAL) project that has received funding from the European Union's Horizon 2020 research and innovation program ​under grant agreement 871029. S. R.-R. was supported by the the FPI fellowship funded by Universidad San Pablo CEU. J.A-H. was supported by the PFIS fellowship co-funded by the FEDER/FSE and the ISCIII

Online Escape Room during COVID-19: A Qualitative Study of Social Education Degree Students’ Experiences

Confinement due to the COVID-19 pandemic has hastened an educational shift from face-to-face to online classrooms. This distanced education seeks to achieve learning goals mediated by technology as they would be achieved in the face-to-face classroom, without ignoring the psychological and social impact that COVID-19 has had on students and teachers. Faced with this situation, the use of online educational escape rooms has been proposed as a motivating strategy for students to review curriculum content in a cooperative and fun way. A qualitative investigation was carried out to explore the perceptions of university students in the Social Education degree program after the implementation of an educational escape room. Our main findings are that most students found that it allowed them to interact with their peers beyond traditional education, that it was useful for their learning and that it was a pleasant activity. However, it was also mentioned that it can be a stressful activity as being an online activity, some students may have connectivity problems. It is concluded that online escape rooms can be active and effective learning strategies for university students

Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects

[Background and Aim] Histological score systems may not fully capture the essential nonalcoholic steatohepatitis (NASH) features, which is one of the leading causes of screening failure in clinical trials. We assessed the NASH distribution and its components across the fibrosis stages and their impact on the prognosis and their relationship with the concept of metabolic-associated fatty liver disease (MAFLD).[Methods] Spanish multicenter study including 1893 biopsy-proven nonalcoholic fatty liver disease (NAFLD) patients from HEPAmet registry. NASH was diagnosed by NAS score ≥4 (including steatosis, ballooning and lobular inflammation) and fibrosis by Kleiner score. The presence of MAFLD was determined. Progression to cirrhosis, first episode of decompensated cirrhosis and death were collected during the follow-up (4.7 ± 3.8 years).[Results] Fibrosis was F0 34.3% (649/1893), F1 27% (511/1893), F2 16.5% (312/1893), F3 15% (284/1893) and F4 7.2% (137/1893). NASH diagnosis 51.9% (982/1893), and its individual components (severe steatosis, ballooning and lobular inflammation), increased from F0 (33.6%) to F2 (68.6%), and decreased significantly in F4 patients (51.8%) (P = .0001). More than 70% of non-NASH patients showed some inflammatory activity (ballooning or lobular inflammation), showing a similar MAFLD rate than NASH (96.2% [945/982] vs. 95.2% [535/562]) and significantly higher than nonalcoholic fatty liver (NAFL) subjects (89.1% [311/349]) (P < .0001). Progression to cirrhosis was similar between NASH (9.5% [51/539]) and indeterminate NASH (7.9% [25/316]), and higher than steatosis (5% [14/263]) (logRank 8.417; P = .015). Death and decompensated cirrhosis were similar between these.[Conclusions] The prevalence of steatohepatitis decreased in advanced liver disease. However, most of these patients showed some inflammatory activity histologically and had metabolic disturbances. These findings should be considered in clinical trials whose main aim is to prevent cirrhosis progression and complications, liver transplant and death.This project has been partially funded by the ‘Consejería de Salud de la Junta de Andalucía’ (PI-0075-2014) and the ‘Spanish Ministry of Economy, Innovation and Competition, Instituto de Salud Carlos III’ (PI19/01404, PI16/01842, PI17/00535 and GLD19/00100).Peer reviewe